遗传工程国家重点实验室特邀学术报告 Dimiter S. Dimitrov
遗传工程国家重点实验室
遗传学研究所
特邀学术报告
题目:Human monoclonal antibodies against viruses and cancer

报告时间:2013年3月15日 上午10:00

地点:遗传楼后平房 2117会议室


报告人:


Dimiter S. Dimitrov , Ph.D.

Senior Investigator, Tenure, National Cancer Institute, NIH,Bethesda,USA


 

5 Most Significant Publications(corresponding author):

Xiaodong Xiao, Zhongyu Zhu, Jennifer L. Dankmeyer, Michael M. Wormald, Randy L. Fast, Patricia L. Worsham, Christopher K. Cote, Kei Amemiya, Dimiter S. Dimitrov: Human anti-plague monoclonal antibodies protect mice from Yersinia pestis in a bubonic plague model. PLoS ONE, in press.

Chen, W., Zhu, Z., Feng, Y., and Dimitrov, D. S.:  Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers.  PNAS 105(44):17121-6. 2008

Zhu, Z., Chakraborti, S., He, Y., Roberts, A., Sheahan, T., Xiao, X., Hensley, L. E., Prabakaran, P., Rockx, B., Sidorov, I. A., Corti, D., Vogel, L., Feng, Y., Kim, J-O., Wang, L-F., Baric, R., Lanzavecchia, A., Curtis, K. M., Nabel, G. J., Subbarao, K., Jiang, S., and Dimitrov, D. S.: Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. PNAS 104(29): 12123-12128, 2007.

Zhang, M-Y., Vu, B. K., Choudhary, A., Lu, H., Humbert, M., Ong, H., Alam, M., Ruprecht, R. M., Quinnan, G., Jiang, S., Montefiori, D. C., Mascola, J. R., Broder, C. C., Haynes, B. F., and Dimitrov, D. S.: Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody which recognizes a novel conformational epitope on gp41 and lacks reactivity against self antigens. J. Virol. 82(14): 6869-6879, 2008.

Gong, R., Vu, B. K., Feng, Y., Prieto, D. A., Dyba, M. A., Walsh, J. D., Prabakaran, P., Veenstra, T. D., Tarasov, S. G., Ishima, R., and Dimitrov, D. S.: Engineered human antibody constant domains with increased stability. J. Biol. Chem. 284:14203-14210, 2009. 

发布日期:2013/3/15