余龙-遗传工程国家重点实验室

余龙 Long Yu

教授，国家杰出青年基金获得者

Professor，Cheung Kong Scholar，Outstanding Young Scientist of China

Email：longyu@fudan.edu.cn

Ø 主要经历

1970.11-1974.8，中国人民解放军基建工程兵部队，战士、班长

1974.9-1978.2，第一军医大学，本科

1978.3-1982.7，中国人民解放军基建工程兵部队，军医、所长

1982.8-1986.2，中山医科大学，硕士

1986.2-1987.2，中山医科大学第一临床医学院，医师

1987.2-1990.10，中山医科大学，博士

1990.11-1992.10，复旦大学，博士后

1992.11-1993.2，复旦大学，讲师

1993.3-1995.4，复旦大学，副教授

1995-今，复旦大学，教授

1999-2002，复旦大学遗传工程国家重点实验室，常务副主任

2002-2012，复旦大学遗传工程国家重点实验室，主任

Ø Main Experiences

1974-1978，B.A.，First Military Medical University

1985-1990，M.D.，Sun Yat-Sen Medical University

1990-1993，Post-doctoral fellow，Fudan University

1993-1995，Associate professor，Fudan University

1995-present，Professor，Fudan University

1998-2002，Deputy Director，State Key Laboratory of Genetic Engineering

2002-present，Director，State Key Laboratory of Genetic Engineering

Ø 主要科研领域

肝癌发生的分子遗传学机制研究和抗肝癌药物小分子化合物筛选、以及重大疾病相关基因的系统生物学及药物开发研究。

Ø Main Research Fields

Our interest mainly focuses on the molecular genetic mechanisms of HCC progression, screening of small molecules for anti-HCC drugs, as well as systematic biology study and drug development of major disease-related genes.

Ø Selected Publications

1. Jiang, D. K., Sun, J., Cao, G., Liu, Y., Lin, D., Gao, Y. Z., ... & Liu, J. (2013). Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nature genetics, 45(1), 72-75.

2. Xiao, Q., Qu, K., Wang, C., Kong, Y., Liu, C., Jiang, D., ... & Yu, L. (2013). HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas. Gut, 62(3), 440-451.

3. Liu, G., Jiang, S., Wang, C., Jiang, W., Liu, Z., Liu, C., ... & Yu, L. (2012). Zinc finger transcription factor 191, directly binding to β‐catenin promoter, promotes cell proliferation of hepatocellular carcinoma. Hepatology, 55(6), 1830-1839.

4. Huang, W., Ding, L., Huang, Q., Hu, H., Liu, S., Yang, X., ... & Yu, L. (2010). Carbonyl reductase 1 as a novel target of (−)‐epigallocatechin gallate against hepatocellular carcinoma. Hepatology, 52(2), 703-714.

5. Wu, Y., Zuo, J., Ji, G., Saiyin, H., Liu, X., Yin, F., ... & Yu, L. (2009). Proapoptotic function of integrin β3 in human hepatocellular carcinoma cells. Clinical Cancer Research, 15(1), 60-69.